School of Medicine - Medicine

  • Associate Professor
  • LEE, YUNJONG

Journal Articles

  • (2023)  PARIS undergoes liquid–liquid phase separation and poly(ADP-ribose)-mediated solidification.  EMBO REPORTS.  24,  11
  • (2023)  Identification and evaluation of midbrain specific longevity-related genes in exceptionally long-lived but healthy mice.  FRONTIERS IN AGING NEUROSCIENCE.  14,  -
  • (2022)  Pharmacological inhibition of AIMP2 aggregation attenuates ?-synuclein aggregation and toxicity in Parkinson?s disease.  BIOMEDICINE & PHARMACOTHERAPY.  156,  -
  • (2022)  Synthetic Peucedanocoumarin IV Prevents alpha-Synuclein Neurotoxicity in an Animal Model of Parkinson's Disease.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  23,  15
  • (2021)  Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration.  BRAIN.  144,  1
  • (2021)  PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease.  SCIENCE TRANSLATIONAL MEDICINE.  13,  604
  • (2021)  Effects of 1 alpha,25-Dihydroxyvitamin D-3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with PBPK Modeling Approach.  PHARMACEUTICS.  13,  8
  • (2021)  Sensitive electrochemical biosensor combined with isothermal amplification for point-of-care COVID-19 tests.  BIOSENSORS & BIOELECTRONICS.  182, 
  • (2020)  Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death.  SCIENCE SIGNALING.  13,  663
  • (2020)  Differential Effects of 1 alpha,25-Dihydroxyvitamin D-3 on the Expressions and Functions of Hepatic CYP and UGT Enzymes and Its Pharmacokinetic Consequences In Vivo.  PHARMACEUTICS.  12,  11
  • (2020)  Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson's Disease via a Vitamin D Receptor-Dependent Pathway.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  21,  22
  • (2020)  Amyloid-like oligomerization of AIMP2 contributes to alpha-synuclein interaction and Lewy-like inclusion.  SCIENCE TRANSLATIONAL MEDICINE.  12,  569
  • (2020)  Novel Nasal Epithelial Cell Markers of Parkinson's Disease Identified Using Cells Treated with alpha-Synuclein Preformed Fibrils.  JOURNAL OF CLINICAL MEDICINE.  9,  7
  • (2020)  Deubiquitinase USP29 Governs MYBBP1A in the Brains of Parkinson's Disease Patients.  JOURNAL OF CLINICAL MEDICINE.  9,  1
  • (2019)  The regulation of glutamic acid decarboxylases in GABA neurotransmission in the brain.  ARCHIVES OF PHARMACAL RESEARCH.  42,  12
  • (2019)  Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson's Disease.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  20,  21
  • (2019)  Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio.  ADVANCED SCIENCE.  6,  22
  • (2019)  Quantitative analysis of nasal transcripts reveals potential biomarkers for Parkinson's disease.  SCIENTIFIC REPORTS.  9,  999
  • (2019)  Cell-Based Screen Using Amyloid Mimic beta 23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of alpha-Synuclein and Huntingtin Aggregates.  MOLECULES AND CELLS.  42,  6
  • (2019)  Rhododendrin-Induced RNF146 Expression via Estrogen Receptor Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.  20,  7

Patent/Intellectual Property

  • 파킨슨 질환 동물 모델 및 이를 이용한 스크리닝 방법.  10-2018-0135355.  20201229.  KOREA, REPUBLIC OF
  • ZNF146의 인산화-타이로신 잔기 특이적 항체 및 이의 용도.  10-2017-0169065.  20200302.  KOREA, REPUBLIC OF
  • 도파민 신경세포 특이적 발현 제어 시스템.  10-2018-0097376.  20200121.  KOREA, REPUBLIC OF
  • 콧물액을 이용한 파킨슨 질환의 진단 방법, 이를 위한 조성물 및 이를 포함하는 키트.  10-2018-0035157.  20200116.  KOREA, REPUBLIC OF
  • 노화 모델 제조 방법 및 이에 의해 제조된 세포 또는 동물 노화 모델.  10-2017-0139195.  20190819.  KOREA, REPUBLIC OF
  • 퇴행성 뇌질환의 치료 또는 예방용으로서의 RNF146 발현 유도 약학 조성물.  10-2017-0036003.  20181004.  KOREA, REPUBLIC OF
  • 퓨세다노쿠마린 III를 포함하는 퇴행성 뇌질환의 치료 또는 예방용 약학 조성물.  10-2017-0051223.  20181004.  KOREA, REPUBLIC OF
  • 퇴행성 뇌질환 치료제 스크리닝 방법 및 이를 위한 키트.  10-2017-0024563.  20180808.  KOREA, REPUBLIC OF